DATE: |
2009-12-24 11:00 - 12:00 |
PLACE: |
Conference room in the Structural Biology Research Center Bldg. |
TITLE: |
PF Seminar Function and structure of deubiquitinase |
SPEAKER: |
Dr.Masato Akutsu (MRC Laboratory of Molecular Biology) |
LANGUAGE: |
English |
URL: |
http://pfwww.kek.jp/pf-seminar/ |
ABSTRACT: |
Ubiquitin regulates many celler processes as a post-translational modifier. Ubiquitin ligase attaches ubiquitin to the substrate (ubiquitilation) and deubiquitinase reverses ubiquitilation. Recently,
we solved the crystal structure of deubiquitinase. I will talk about the basic concept of ubiquitilation and deubiquitilation with our structure. |