One of the most promising way to detect dark matter is to look for its annihilation or decay products among cosmic-rays (indirect detection). Recently, more and more interesting results are reported from measurements of cosmic-rays such as gamma-rays, neutrinos, positrons, antiprotons, etc. In this talk, I will especially focus on gamma-ray search from dwarf spheroidal galaxies (dSphs). Though the dSphs is one of the best target for the indirect detection, there remains large uncertainty on the estimation of dark matter profile around the dSphs. I will show how the constraints fluctuate under conservative estimation of the profile and discuss the future prospect of the constraints.