2025.05 -2027.03 JSPS Bilateral Collaborations: Joint Research Project with TÜBİTAK (Turkey)(Principal Investigator)
A novel method to mix and freeze protein samples in milliseconds for time-resolved cryo-EM.
2024.10 – 2029.03 Interdisciplinary Domain Expansion Hub Formation Program (Co-Investigator)
Formation of a Multi³ Structural Science Center with Multiple Probes, Multiple Targets, and Multiple Hierarchies.
Ryuichi Kato
2023.04 - 2028.03 Grant-in-Aid for Scientific Research (B) (Co-Investigator)
Molecular basis and physiological significance of O-mannosyl glycans in mammals
Masato Kawasaki
2022.04 -2027.3 AMED Basis for Supporting Innovative Drug Discovery and Life Science Research (Co-Investigator)
Support of production and structural analysis of disease-related membrane proteins.
2025.04-2028.03 Grant-in-Aid for Scientific Research (C) (Principal Investigator)
Cryo-EM sample freezing technique using the antifreeze protein.
2026.04-2029.03 Grant-in-Aid for Scientific Research (B) (Co-Investigator)
Atomic-level analysis of structural and functional changes of hair follicle proteins under selective citrullination.
Mikio Tanabe
2026.04 - 2031.03 Grant-in-Aid for Challenging Research (Pioneering) (Principal Investigator)
Converting drug-resistant bacteria to drug-sensitive bacteria using artificial proteins: Seal the exit, Block drug pathways, and Prevent assembly
2024.04 - 2028.03 Grant-in-Aid for Scientific Research (B) (Principal Investigator)
Deorphanization of MFS-type Multidrug Efflux Transporters: Dual Inhibition of Drug Efflux and Physiological Substrate Transport
2025.04 - 2027.03 Collaboration grant for the Network Joint Research Center (NJRC) for Materials and Devices: Crossover Joint Research Program(Principle Investigator)
Structural analysis and functional regulation of multidrug efflux pumps using artificially designed proteins and small molecules developed with machine learning
Toshio Moriya
2023.04 -2026.03 Grant-in-Aid for Scientific Research (B) (Principal Investigator)
Analyzing the continuous dynamics of protein structures through single-molecule structure analysis with cryogenic electron microscopy
Simon Miller
2026.04 -2029.03 Grant-in-Aid for Scientific Research (C) (Principal Investigator)
Circadian clock regulation of GTP signalling.
Masahide Hikita
2026.04 -2029.03 Grant-in-Aid for Challenging Research (Exploratory) (Principal Investigator)
Visualization of Reactions in Protein Crystals: Innovative in-situ Analysis via Vapor-Flow Soaking and Microspectroscopy.
Miki Senda
2026.07-2027.03 TIA "Kakehashi" (Principal Investigator)
CPractical Implementation of an Interactive X-ray Crystallography Manual to Connect Beginners and Experts
2024.04 - 2027.03 Grant-in-Aid for Scientific Research (C) (Principal Investigator)
Structural analysis to elucidate the activation mechanism of Calmodulin-Dependent Kinase and Its application to the treatment of heart failure
Satomi Inaba
2026.07ー2029.03 Takeda Science Foundation Life Science Research Grants (Principal Investigator)
Uncovering the spatial arrangement and functional regulation of bacterial membrane transporters during drug resistance acquisition
2024.04 - 2027.03 Grant-in-Aid for Scientific Research (C) (Principal Investigator)
Substrate recognition and uptake mechanism of antimicrobial peptide transporters
Tsukasa Nakamura
2023.08 - 2025.03 Grant-in-Aid for Early-Career Scientists (Principal Investigator)
Advanced utilization of cryo-electron microscopy data using deep learning
Finished projects
2025.1 - 2025.12 Exploratory Research Grant by Shionogi
Therapeutic resistance and aggressive malignancy in glioblastomas: the contribution of GTP metabolism through regulation by IMPDH2
(Principle Investigator:Mikio Tanabe)
2022.04 -2025.06 NIH Research Project Grant
Therapeutic resistance and aggressive malignancy in glioblastomas: the contribution of GTP metabolism through regulation by IMPDH2
(Co-Investigator: Toshiya Senda)
2022.04 – 2025.03 Grant-in-Aid for Scientific Research (B)
Mechanistic study of quaternary structure changes of a LysR- type transcriptional regulator
(Principal Investigator: Toshiya Senda)
2022.10 - 2025.03 AMED Practical Research Project for Life-Style related Diseases including Cardiovascular Diseases and Diabetes Mellitus (Co-Investigator)
Development of a comprehensive treatment system for diabetes and obesity-related diseases by targeting metabolite sensor molecules
(Co-Investigator：Ryuichi Kato)
2021.04 – 2024.03 Grant-in-Aid for Scientific Research (C)
A novel method for preparing cryo-EM grids by using an amphipathic peptide
(Principal Investigator: Masato Kawasaki)
2023.04 - 2025.03 NJRC Network Joint Research Center for Materials and Devices
Elucidation of the original physiological Functions of drug efflux transporters by AI-based structural and metabolic pathway analysis
(Principle Investigator:Mikio Tanabe)
2023.08 - 2025.03 Grant-in-Aid for Research Activity Start-up
Molecular Mechanism of Histone Chaperone Activity Based on IDR Structural Plasticity of NPM1
(Principal Investigator：Genoveso Michelle Jane)
2015.04 - 2018.03 Grant-in-Aid for Scientific Research on Innovative Areas, Challenging Exploratory Research
Structural anlaysis of membrane protein complexes using S-SAD method
(Principal Investigator: Ryuichi Kato)
2015.04 - 2018.03 Grant-in-Aid for Scientific Research on Innovative Areas, Scientific Research (C)
Investigation of membrane curveture formation by SYLF domain
(Principal Investigator: Masato Kawasaki)
2015.04 - 2017.03 Grants-in-Aids for Scientific research (KAKENHI), Grant-in-Aid for Scientific Research on Innovative Areas, Challenging Exploratory Research
A new frontier of structural biology using ultra high speed micro pixeled detector
(Co-Investigator: Nobutaka Shimizu)
2015.04 - 2018.03 Grant-in-Aid for Scientific Research on Innovative Areas, Scientific Research (C)
Invetigation of molecular mechanism of the regulation of transcription by Nuclear Receptor
(Principal Investigator: Fumiaki Yumoto)
2015.08 - 2017.03 Grant-in-Aid Research Activity Start-up
Investigation of molecular mechanism of transphosphorylation by a phosphatidylinositol kinase
(Principal Investigator: Tomomi Sato)
2014.04 - 2016.03 Grant-in-Aid for Scientific Research on Innovative Areas, Challenging Exploratory Research (Principal Investigator)
Establish a method of increasing the success rate of crystallization under Anaerobic conditions
(Principal Investigator: Miki Senda)
2014.04 - 2016.03 Grant-in-Aid for Young Scientists (B)
Structural and functional relationship of glycosyl transferase causing Muscular Dystrophy
(Principal Investigator: Naoyuki Kuwabara)
2013.10 - 2018.03 Photon and Quantum Basic Research coordinated development program by MEXT
Investigation of redox dependent affinity regulating mechanism of electron-transfer protein
(Principal Investigator: Toshiya Senda)
2013.08 - 2015.03 Grant-in-Aid Research Activity Start-up
Analysis in molecular mechanism of transcriptional activation of LRH-1 by beta-catenin
(Principal Investigator: Fumiaki Yumoto)
2013.10 - 2017.03 Strategic Basic Research Programs PRESTO
Analysis of the regulatory mechanisms of chromatin transcription through the strucural analysis of TFIID
(Principal Investigator: Naruhiko Adachi)
2012. - 2016. Platform for Drug Discovery, Informatics, and Structural Life Science (PDIS) (Analysis Core - Representative)
Analysis and Users support by PDIS - accelating protein structural life science analysis and enhancement of the state-of-the-art techonology
(Principal Investigator: Toshiya Senda)
2012. - 2016. Platform for Drug Discovery, Informatics, and Structural Life Science (PDIS) (Analysis Core - Protein production section - Representative)
Establishing the Automated high-throght put crystallization pipleline and users support system
(Principal Investigator: Ruichi Kato)
2012.06 - SACLA-SFX Project (Co-Investigator, KEK-Representative)
Rapid Structure determination system for Drug-target proteins using the X-ray free electron laser
(Principal Investigator: Fumiaki Yumoto)
2012.06 - SACLA-SFX Project (Co-Investigator, KEK-Representative)
Rapid Structure determination system for Drug-target proteins using the X-ray free electron laser
(Principal Investigator: Fumiaki Yumoto)
2012.10 - 2015.03 Grant-in-Aid for Scientific Research on Innovative Areas, Scientific Research (B)
Mechanistic analyses of chromatin structural changes through the structure of TFIID
(Principal Investigator: Toshiya Senda)
2012.06 - 2017.03 Grants-in-Aids for Scientific research (KAKENHI), Grant-in-Aid for Scientific Research on Innovative Areas
New aspect of Ubiqutin system: is enormous roles in protein regulation
(Co-Investigator:Ryuichi Katot)
2011.04 - 2016.03 Grant-in-Aid for Scientific Research on Innovative Areas, Scientific Research (S)
"A new frontier of structural biology using ultra high speed micro pixeled detector
(Co-Investigator: Nobutaka Shimizu & Naohiro Matsugaki)
2007. - 2011. Targeted Proteins Research Progam
Project A: Structural and Functional Analysis of Protein Complexes Regulating Vesicular Transport
Project C: Development of Synchrotron X-ray Crystallography Techniques Targeting Difficult-to-Analyze Proteins
(Principle Investigator: Soichi Wakatsuki)
2006. - 2008. Japan-UK Science & Innovation Collaboration
Development of Fundamental Technologies for Membrane Protein Crystallography Using Synchrotron Radiation
(Principle Investigator: Soichi Wakatsuki)
2004. - 2007. The development of systems and technology for advanced measurement and analysis
Development of a Next-Generation Structural Analysis System for Biological Supramolecular Complexes Using X-ray HARP-FEA
2006. - 2006. Protein Analysis Platform Technology Development Project
2002. - 2006. Protein 3000
2001. - 2003. Special Coordination Funds for Promoting Science and Technology
Development of Infrastructure Contributing to the Advancement of Protein X-ray Crystallography
