We, Synchrotron Radiation Science Divisions 1 & 2, aim to open up new scientific fields using synchrotron radiation and recently introduced cryo-electron microscopy (cryo-EM), and to turn out researchers who can be actively involved in a wide range of fields in Japan and abroad in future. Therefore, we are looking for researchers who are willing to produce outstanding research achievements through making the best use of the position as a member of IMSS, and to contribute to the development of synchrotron radiation science from a broad perspective, regardless of their field of expertise.
The researchers in the Structural Biology Research Section of Synchrotron Radiation Science Division 2 have organized the Structural Biology Research Center (SBRC) with researchers from other divisions to promote structural biology research. The SBRC conducts structural biology research using synchrotron radiation X-rays for crystal structure analysis and cryo-electron microscopy. We combine experimental techniques of biochemistry and molecular biology to elucidate the molecular mechanisms of functional expression of biological macromolecules. In addition, we have collaborated with a wide range of life science researchers to elucidate the biological significance of target biological macromolecules.
【HP of SBRC】 https://www2.kek.jp/imss/sbrc/eng/
The successful candidate is expected to conduct structural studies of biological macromolecules, especially on membrane proteins, using crystallography and cryo-electron microscopy in collaboration with domestic and international researchers. He/she is also expected to provide user support and participate in the technical advancement of experiments from sample preparation to structural analysis for X-ray crystallography and cryo-EM operated as an Inter-University Research Institute Corporation and to open up a new research field of membrane proteins. Since the SBRC is also involved in the BINDS (Basis for Supporting Innovative Drug Discovery and Life Science Research) project of the Japan Agency for Medical Research and Development (AMED) to support domestic life science researchers and to develop advanced methods in structural biology, he/she will participate in the project and be involved in relevant research, user support, and management. In addition, the SBRC has a strong commitment to international activities. Therefore, we strongly desire individuals who can strengthen our links with foreign countries.
